RecruitingNCT05164328

Prospective Athlete's Heart Study

Prospective Athlete's Heart Study: Long-term Assessment of the Determinants of Cardiac Remodelling and Its Clinical Consequences in Endurance Athletes


Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

450 participants

Start Date

Jun 23, 2015

Study Type

OBSERVATIONAL

Conditions

Summary

The Pro@Heart (Prospective Athlete's Heart) study is an international multicentre long-term prospective trial. The primary objective of the Pro@Heart study is to investigate the impact of training load (i.e. accurately evaluated in term of type, frequency, duration and intensity) and genotype on the variability of structural, functional and electrical exercise induced cardiac remodeling (EICR) in young competitive endurance athletes. The second objective is to determine how EICR, training load and genotype are associated with physical performance, health benefits and cardiac pathology (e.g. exercise-related cardiomyopathies and arrhythmias) during follow-up over several decades.


Eligibility

Min Age: 14 YearsMax Age: 23 Years

Inclusion Criteria8

  • Males and females aged 14-23 years old
  • Athletes competing in endurance sports at national or international level for at least 2 years. Sports include:
  • Triathlon
  • Cycling
  • Distance running (≥ 1500 meters)
  • Rowing
  • Swimming
  • Non athletes engaged in \< 3 hours per week of physical activity

Exclusion Criteria3

  • Medical history of cardiovascular disease
  • Current smoker of past history of smoking
  • Diabetes mellitus

Interventions

OTHERNo intervention

No intervention


Locations(4)

Baker Heart and Diabetes Institute

Melbourne, Victoria, Australia

UZ Antwerpen

Edegem, Antwerp, Belgium

Jessa Ziekenhuis Hasselt

Hasselt, Limburg, Belgium

UZ Leuven

Leuven, Vlaams Brabants, Belgium

View Full Details on ClinicalTrials.gov

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NCT05164328