RecruitingNCT05164328

Prospective Athlete's Heart Study

Prospective Athlete's Heart Study: Long-term Assessment of the Determinants of Cardiac Remodelling and Its Clinical Consequences in Endurance Athletes

Sponsor

Universitaire Ziekenhuizen KU Leuven

Enrollment

450 participants

Start Date

Jun 23, 2015

Study Type

OBSERVATIONAL

Conditions

Athlete Heart

Summary

The Pro@Heart (Prospective Athlete's Heart) study is an international multicentre long-term prospective trial. The primary objective of the Pro@Heart study is to investigate the impact of training load (i.e. accurately evaluated in term of type, frequency, duration and intensity) and genotype on the variability of structural, functional and electrical exercise induced cardiac remodeling (EICR) in young competitive endurance athletes. The second objective is to determine how EICR, training load and genotype are associated with physical performance, health benefits and cardiac pathology (e.g. exercise-related cardiomyopathies and arrhythmias) during follow-up over several decades.

Eligibility

Min Age: 14 YearsMax Age: 23 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking heart health in elite young endurance athletes (triathletes, cyclists, rowers, swimmers, distance runners) over time to better understand how intense training affects the heart — and distinguish healthy athletic adaptation from warning signs of disease. Non-athletes are also being enrolled for comparison. **You may be eligible if...** - You are 14–23 years old - You are an elite athlete competing nationally or internationally in triathlon, cycling, distance running (≥1500m), rowing, or swimming for at least 2 years - OR you are a non-athlete doing fewer than 3 hours of physical activity per week **You may NOT be eligible if...** - You have a history of heart or cardiovascular disease - You are a current or former smoker - You have diabetes Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERNo intervention

No intervention

Locations(4)

Baker Heart and Diabetes Institute

Melbourne, Victoria, Australia

UZ Antwerpen

Edegem, Antwerp, Belgium

Jessa Ziekenhuis Hasselt

Hasselt, Limburg, Belgium

UZ Leuven

Leuven, Vlaams Brabants, Belgium

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05164328

Related Trials

Interaction Between Intraventricular Flow and Cardiac Mechanics Using 3D Echocardiography in Athletes and Sedentary Subjects

NCT073639932 locations

Risk of Sudden Cardiac Death in UN Athletes

NCT065182521 location