RecruitingNCT05167487

Pathological Response After Neoadjuvant Treatment on NSCLC

Retrospective Observational Study of Resectable Stage IIIA Non-small Cell Lung Cancer Patients: Pathological Response After Neoadjuvant Treatment and Patient Outcomes


Sponsor

Fundación GECP

Enrollment

150 participants

Start Date

Dec 13, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

This is a non-interventional, observational, multicenter and retrospective study. Being limited to the collection of patient data already filled in the Tumor Thoracic Registry data base and the data from stage IIIA clinical trials case report forms.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Patients with resectable stage IIIA disease (according to American Joint Committee on Cancer \[AJCC\] lung cancer edition 7 or 8) who were included in the Tumor Thoracic Registry data base and in stage IIIA clinical trials which the sponsor is Fundación GECP.
  • Patients with histologically N2 involvement confirmed
  • Patients diagnosed as stage IIIA from 2010 and 2017
  • Patients who have received neoadjuvant platinum-based treatment and surgery
  • Age ≥ 18 years at time of study entry
  • PET /TC at diagnosis

Exclusion Criteria3

  • Patients who received chemoradiotherapy neoadjuvant treatment
  • Patients who were not resected after neoadjuvant treatment
  • Patients who were diagnosed after June 2017

Interventions

DRUGCisplatin

Route of administration: Intravenous infusion. Neoadjuvant chemotherapy is often given 2 to 4 months before surgery.

DRUGCarboplatin

Route of administration: Intravenous infusion. Neoadjuvant chemotherapy is often given 2 to 4 months before surgery.


Locations(17)

Hospital Universitario De A Coruna

A Coruña, A Coruña, Spain

Hospital General Universitario de Alicante

Alicante, Alicante, Spain

ICO Badalona, Hospital Germans Trias i Pujol

Badalona, Barcelona, Spain

Hospital Vall d'Hebron

Barcelona, Barcelona, Spain

Hospital de la Santa Creu i Sant Pau

Barcelona, Barcelona, Spain

ICO Hospitalet

L'Hospitalet de Llobregat, Barcelona, Spain

Hospital Universitario Insular de Gran canaria

Las Palmas de Gran Canaria, Gran Canaria, Spain

Hospital Dr. Negrín

Las Palmas de Gran Canaria, Las Palmas, Spain

Hospital Clínico San Carlos

Madrid, Madrid, Spain

Hospital Universitario Fundación Jiménez Díaz

Madrid, Madrid, Spain

Hospital 12 De Octubre

Madrid, Madrid, Spain

Hospital Universitario la Paz

Madrid, Madrid, Spain

Hospital Universitario Puerta de Hierro

Majadahonda, Madrid, Spain

Hospital Universitario Regional de Málaga

Málaga, Málaga, Spain

Complejo Hospitalario Universitario de Vigo

Vigo, Pontevedra, Spain

Hospital Universitario La Fe

Valencia, Valencia, Spain

Hospital Universitario Cruces

Barakaldo, Vizcaya, Spain

View Full Details on ClinicalTrials.gov

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NCT05167487