RecruitingPhase 2NCT05177510

Mifepristone Outpatient Labour Induction


Sponsor

Chelsea and Westminster NHS Foundation Trust

Enrollment

400 participants

Start Date

Aug 25, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The number of women having an induction of labour is increasing and is currently used in 33% of pregnancies for a range of medical reasons. The majority of women are admitted to hospital to have their labour induced, using methods which are protracted and associated with a poor birth experience, making them both costly and unpopular. Further, current methods of outpatient induction are unsuitable, unsafe and/or have a poor acceptability. The COVID-19 pandemic has driven a reduction in the number of face-to-face interactions taking place across all areas of medicine. Proving the efficacy and safety of Mifepristone would significantly reduce pre-labour admission rates and hospital length of stay for pregnant women, who are at particularly higher risk of COVID-19, and reduce delivery costs.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Mifepristone and a drug called Placebo for people with labor, induced. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGMifepristone

Progestin Antagonist

DRUGPlacebo

Placebo


Locations(1)

Chelsea and Westminster Hospital

London, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT05177510


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