RecruitingNCT05179486

Molecular Epidemiology of Biliary Tree Cancers


Sponsor

M.D. Anderson Cancer Center

Enrollment

1,500 participants

Start Date

Sep 25, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

This study is to learn if certain risk factors (environmental, viral, behavioral, medical, and dietary), tumor markers, and genetic changes can predict the development and outcome of biliary tree cancers. Establishing biomarkers models from patients may help doctors to further understand how biliary tree cancer is affected by different treatments, and why some people's cancer responds differently than others.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is collecting samples and health information from patients with cancers of the bile ducts or gallbladder to identify the molecular and genetic factors that cause these cancers. It also includes healthy volunteers and people with chronic liver disease for comparison. **You may be eligible if:** - You have been diagnosed with cholangiocarcinoma (bile duct cancer) or gallbladder cancer, confirmed by pathology or imaging - You are a healthy person with no personal or current history of cancer (for the control group) - You have chronic liver disease but no liver cancer (for the liver disease control group) - You can be located anywhere in the world — there are no age, gender, or race restrictions **You may NOT be eligible if:** - There are no specific exclusion criteria for this study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Undergo collection of tissue, and blood

OTHERQuestionnaire Administration

Complete questionnaire


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

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NCT05179486


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