SPECT/CT Bone Scan Quantification Surgery
Predictive Performance of SPECT/CT Bone Scan Quantification Before Lumbar Arthrodesis
Central Hospital, Nancy, France
70 participants
Apr 29, 2022
INTERVENTIONAL
Conditions
Summary
The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.
Eligibility
Inclusion Criteria6
- Persons with back pain for at least 3 months (presumed to be due to degenerative disc disease or spondylolisthesis).
- Persons who have received full information about the organisation of the research and have signed the informed consent and :
- Age ≥ 18 years, having read and understood the information document.
- Affiliated to a social security scheme.
- Lumbar arthrodesis involving a maximum of 2 floors.
- Standardized lumbar arthrodesis surgery performed by one of the three senior neurosurgeons of the neurosurgery department of the Nancy CHRU, using similar surgical techniques.
Exclusion Criteria9
- Low back pain of neuropathic origin. The Neuropathic Pain Scale 4 questionnaire is used to diagnose neuropathic pain (score is ≥ 4/10)
- History of lumbar spine surgery
- Presence of other pathologies responsible for lumbar pain (multistage discopathies, ankylosing spondylitis, spondylodiscitis, rheumatoid arthritis, vertebral compression, vertebral metastasis, narrow lumbar canal, scoliosis, spondylolisthesis by isthmic lysis)
- Pregnant women or women of childbearing age without suitable contraception or nursing mothers.
- Unstable medical condition and/or inability to remain immobile in supine position during recordings.
- Known allergy to any component of the radiopharmaceutical (TECHNESCAN HDP).
- Person referred to in Articles L. 1121-5, L. 1121-7 and L1121-8 of the Public Health Code.
- Persons deprived of their liberty by a judicial or administrative decision, persons under psychiatric care by virtue of Articles L. 3212-1 and L. 3213-1.
- Persons of full age who are unable to express their opposition.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Persons to be operated on for lumbar arthrodesis by the neurosurgery team of the Nancy CHRU and respecting the eligibility criteria (including a score of neuropathique pain scale \< 4, see non-inclusion criteria), will be proposed to participate in the study neuropathic pain If they give their oral agreement to the neurosurgeon, a request for a bone scan will be sent to the nuclear medicine department of the Nancy-Brabois Hospital. The patients will fill pain scales before and after surgery (ODI and NS)
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05183542