RecruitingNot ApplicableNCT05188014

Exercise and the Menstrual Cycle in Type 1 Diabetes

Effects of the Menstrual Cycle on Blood Glucose Changes During Exercise in Women With Type 1 Diabetes Using Oral Contraceptives


Sponsor

University of Alberta

Enrollment

15 participants

Start Date

Mar 15, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Female participants with type 1 diabetes using oral contraceptives will be asked to wear a continuous glucose monitor for at least three days on two separate occasions (once during the last week of active pills and once during the no pill/placebo pill phase of the menstrual cycle). An exercise session (45 minutes of aerobic exercise at 60% VO2peak on a cycle ergometer) will take place at 5 pm on the second day of glucose monitoring.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how different phases of the menstrual cycle affect blood sugar responses to exercise in women with type 1 diabetes who use oral contraceptives. Understanding this connection could help improve exercise safety guidelines for this group. **You may be eligible if...** - You have been living with type 1 diabetes for at least 1 year - You have regular menstrual cycles - You are using monophasic oral contraceptives - You live in or near Edmonton, Alberta and can visit the University of Alberta lab **You may NOT be eligible if...** - Your HbA1c is above 9.9% (indicating very poorly controlled diabetes) - You have frequent, unpredictable low blood sugar episodes - You have recently changed your insulin management approach - You use an automated insulin delivery system - You have high blood pressure, heart disease, or significant diabetes complications such as severe nerve damage or active eye disease - You have a musculoskeletal condition that prevents exercise Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALLuteal Phase Aerobic Exercise

Participants will perform 45 minutes of moderate (60% VO2peak) aerobic exercise on a cycle ergometer during the last week of active pill consumption.

BEHAVIORALFollicular Phase Aerobic Exercise

Participants will perform 45 minutes of moderate (60% VO2peak) aerobic exercise on a cycle ergometer within 5 days of starting their menses.


Locations(1)

Alberta Diabetes Institute

Edmonton, Alberta, Canada

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NCT05188014


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