RecruitingNot ApplicableNCT05188027

Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes

Acute Glycemic Effects of Aerobic and Resistance Exercise in Post-menopausal Women With Type 1 Diabetes


Sponsor

University of Alberta

Enrollment

20 participants

Start Date

Nov 16, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Participants will be asked to wear a continuous glucose monitor for at least three days on three separate occasions. One testing session will be a no-exercise resting control session (90 minutes). One will be a moderate aerobic exercise session (30 minutes of exercise, 60 minutes of recovery), and the third will be a moderate weight-lifting session (\~30 minutes of exercise, 60 minutes of recovery).The investigators will measure changes in blood glucose during exercise by drawing blood during and after exercise. Post-exercise glucose trends will be examined using continuous glucose monitoring.


Eligibility

Sex: FEMALEMin Age: 45 YearsMax Age: 75 Years

Inclusion Criteria4

  • type 1 diabetes, diagnosed for at least one year
  • post-menopause (at least one year since last menstrual period), or have had a hysterectomy and bilateral salpingo oophorectomy
  • able to perform aerobic and resistance exercise
  • able to visit the lab in Edmonton, Alberta (University of Alberta)

Exclusion Criteria11

  • HbA1c \> 9.9 %
  • frequent and unpredictable hypoglycemia
  • change in insulin management strategy within the last 2 months
  • blood pressure \> 140 / 95
  • severe peripheral neuropathy
  • history of cardiovascular disease
  • musculoskeletal injuries interfering with exercise performance
  • use of medications (other than insulin) that affect glucose metabolism
  • BMI \> 30 kg/m2
  • smoking
  • moderate to high alcohol intake (\> 2 drinks/day)

Interventions

OTHERAerobic Exercise

Walking at 60% of maximal aerobic capacity on a treadmill

OTHERResistance Exercise

Performing one set of 10 repetitions of 10 different weight-lifting exercises

OTHERNo exercise

Participants will rest in a supine position for 30 minutes.


Locations(2)

Alberta Diabetes Institute

Edmonton, Alberta, Canada

Institut de recherches cliniques de Montréal

Montreal, Quebec, Canada

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NCT05188027


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