RecruitingPhase 2NCT05190991

Safety and Efficacy of RPH-104 Used to Prevent Recurrent Fever Attacks in Adult Patients With Colchicine Resistant or Colchicine Intolerant Familial Mediterranean Fever

An International Multicenter Open-label Clinical Study of the Safety and Efficacy of RPH-104 for Prevention of Recurring Attacks in Adult Subjects With Familial Mediterranean Fever With Resistance to or Intolerance of Colchicine


Sponsor

R-Pharm International, LLC

Enrollment

60 participants

Start Date

Oct 5, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to assess safety and efficacy of the long-term treatment with RPH-104 at doses of 80 or 160 mg once every 2 weeks (q2w) in patients with familial Mediterranean fever (FMF) with colchicine resistance or intolerance (i.e. colchicine resistant, crFMF), who completed the core study, during which they received at least one dose of RPH-104 (i.e. study patient population).


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called RPH-104 for people with fmf and familial mediterranean fever. The study is currently recruiting participants at 8 locations. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BIOLOGICALRPH-104

solution for subcutaneous administration 40 mg/mL, 2 mL in the 4-mL glass vial


Locations(8)

Center of Medical Genetics and Primary Health Care LLC

Yerevan, Armenia

FSBEI HE First Moscow State Medical University named after I.M. Sechenov

Moscow, Russia

Moscow Multidisciplinary Scientific and Clinical Center named after S.P. Botkin

Moscow, Russia

Medical Technologies Ltd.

Saint Petersburg, Russia

Terafarm, Llc

Stavropol, Russia

Hacettepe University Faculty of Medicine

Ankara, Turkey (Türkiye)

Istanbul University Istanbul Faculty of Medicine

Istanbul, Turkey (Türkiye)

Istanbul University Cerrahpasa Faculty of Medicine

Istanbul, Turkey (Türkiye)

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05190991


Related Trials