RecruitingNot ApplicableNCT05194254

MRI-Eye Tracking Pairing, a Tool for Assessing Social Cognition in Children With ASD


Sponsor

Centre Hospitalier Universitaire, Amiens

Enrollment

68 participants

Start Date

Jan 4, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Most studies use static visual percepts that are less representative of joint attention versus an ecological environment. This has the consequence of decreasing the perception of an interaction with a social partner, which is an essential step in achieving joint attention. The originality of this study is to improve the design of visual percepts (in the form of video) in order to mimic an ecological environment as much as possible by using MRI-ET coupling. The second originality of this study is the longitudinal exploration of the neurodevelopment of social cognition in autistic children. Studies by the Redcay and Oberwelland teams observe different activations at different ages. The hypothesis is that the perception of joint attention varies over time in people with ASD. To date, there are no studies to determine the influence of childhood neurodevelopment in autistic people on the perception of joint attention. It would be unprecedented to use the MRI-ET pairing as a tool for assessing social cognition as a function of the development of children with ASD.


Eligibility

Min Age: 10 YearsMax Age: 20 Years

Plain Language Summary

Simplified for easier understanding

This study pairs brain MRI scans with eye-tracking technology to better understand social cognition in children and adolescents with Autism Spectrum Disorder (ASD). It compares results between young people with ASD and those with typical development to identify brain and behavioral patterns linked to social processing differences. You may be eligible if: - You are between 10 and 20 years old - You have a diagnosis of ASD (CARS score 30 or higher) or are part of the typical development control group (CARS below 30) - You (and your legal guardian) can give written informed consent - You are affiliated with social security - You have no contraindications to MRI You may NOT be eligible if: - You are outside the 10–20 age range - You have a contraindication to MRI (pacemaker, metal implants, claustrophobia, etc.) - You weigh more than 140 kg - You are pregnant or breastfeeding - You are under guardianship or deprived of liberty Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERMRI-ET

coupled fMRI and Eye Tracking tools


Locations(1)

CHU Amiens Picardie

Amiens, Picardie, France

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NCT05194254


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