RecruitingNot ApplicableNCT05205174

Depth Electrode Detection of Cortical Spreading Depolarization After Traumatic Brain Injury

Sponsor

University of Minnesota

Enrollment

15 participants

Start Date

Apr 3, 2025

Study Type

INTERVENTIONAL

Conditions

TBI (Traumatic Brain Injury)

Summary

Preliminary evaluation of depth electrode recording and novel algorithms to determine Cortical Spreading Depolarization's (CSD) following traumatic brain injury (TBI) requiring neurosurgical intervention.

Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called depth electrodes for people with tbi (traumatic brain injury). The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEdepth electrodes

The study will be conducted at a single center, in TBI patients requiring neurosurgical intervention in the form of EVD placement. During neurosurgical intervention at the bedside in the Intensive Care Unit (ICU), a single depth electrode will be placed in the brain adjacent to the EVD catheter in the same burr hole. After EVD and depth electrode placement, continuous recording of ECoG activity as well as relevant physiological parameters will be performed for the duration of clinically indicated invasive neuromonitoring in accordance with the standard of care for TBI patients. A single recording station is currently available for data collection, therefore, with an anticipated average recording period of 14 days, the study will take greater than 210 days to complete for a total of 15 patients.