RecruitingNot ApplicableNCT05206682

Comparison of the Therapeutic Effects of Vaginal Repair With Leuprorelin and Vaginal Repair in the Treatment of Cesarean Section Scar Defect


Sponsor

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Enrollment

94 participants

Start Date

May 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

GnRH-a will be used to postpone period after vaginal repair for Cesarean Section Scar Defect(CSD) patients with adenomyosis which will be compared with CSD patients with adenomyosis who receive transvaginal surgery without GnRH-a, whether delayed period improving the CSD prognosis will be assessed.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two treatments for women who have a defect in their uterus scar from a prior C-section (called Cesarean Scar Defect or CSD) along with a condition called adenomyosis, which causes heavy or prolonged periods. It compares surgery alone versus surgery combined with a hormone injection (leuprorelin) to see which works better. You may be eligible if... - You are a woman between 18 and 50 years old - You have been diagnosed with CSD and adenomyosis - Your periods last more than 10 days or you have abnormal uterine bleeding - The remaining muscle layer at the scar site is less than 3mm thick - Your blood sugar and insulin levels are in the normal range You may NOT be eligible if... - Your diagnosis is uncertain - You have a malignant tumor - You have severe liver, kidney, heart, or lung disease - You are pregnant - You have a mental illness - You are allergic to leuprorelin Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLeuprorelin

Leuprorelin will be used to postpone period after vaginal repair.


Locations(1)

Shanghai Jiaotong University xinhua hospital

Shanghai, Shanghai Municipality, China

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NCT05206682


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