RecruitingNCT05207046

The ACCESSIT Study

Role of ACCESsory Muscles in Mechanically Ventilated Patients After Spinal Cord Injury and Trauma: a Physiological Study - The ACCESSIT Study


Sponsor

Unity Health Toronto

Enrollment

30 participants

Start Date

Dec 17, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The study is designed to characterize and monitor the structure, degree of activation and function of the different respiratory muscles during mechanical ventilation after spine trauma and spinal cord injury.


Eligibility

Min Age: 16 Years

Inclusion Criteria4

  • Presence of traumatic spine lesion (with and without spinal cord injury)
  • Requiring invasive mechanical ventilation, via oro-tracheal or tracheostomy tube,
  • years of age or older
  • Patient or substitute decision maker able to provide consent

Exclusion Criteria3

  • Expected withdrawal of treatments within 24 hours of screening
  • Chronic respiratory failure already treated with mechanical ventilation before the injury
  • Documented pre-existing neuromuscular diseases

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Interventions

OTHERMechanical Ventilation

Patients will be assessed and measurements will be taken during controlled ventilation (most likely \<72 hours of ICU admission), during partially assisted ventilation, and until spontaneous unassisted breathing is reached.


Locations(1)

Unity Health Toronto - St. Michael's Hospital

Toronto, Ontario, Canada

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NCT05207046


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