General Anesthetics-related Changes in Prefrontal EEG During Pediatric Surgical Anesthesia
Peking University First Hospital
366 participants
Jun 1, 2022
OBSERVATIONAL
Conditions
Summary
The change profiles of indices derived from pEEG such as phase-amplitude coupling and bicoherence based on individual general anesthetics in children have not been examined in previous literature. Whether those indices have the abilities to predict individual drug-related anesthesia depth in children need to be explored.
Eligibility
Inclusion Criteria1
- patients aged 0-18 years, American Society of Anesthesiologists Physical Status I-II, scheduled for elective surgery in Peking University First Hospital.
Exclusion Criteria9
- Preterm patients;
- Height and weight not within the standard ranges for respective ages;
- Surgery for head or heart;
- Patients with muscular, neurologic or psychiatric diseases;
- Patients with Congenital anomaly or hereditary diseases;
- Patients with medication abuse;
- Allergy to medication including propofol, sevoflurane, and ketamine;
- Allergy to beans;
- Refusal to participate the study by guardians.
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
General anesthesia is induced and maintained mainly with propofol.
General anesthesia is induced and maintained mainly with sevoflurane.
General anesthesia is induced mainly with S-ketamine and maintained mainly with propofol.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05210764