RecruitingNCT05219851

The Risk Factors for Acute Radiation Pneumonitis in Patients With Prior Receipt of Immune Checkpoint Inhibitors

The Risk Factors for Acute Radiation Pneumonitis in Patients With Prior Receipt of Immune Checkpoint Inhibitors.in Real-world Clinical Practice: a Multicenter, Prospective, Open, Non-interventional Study


Sponsor

Hubei Cancer Hospital

Enrollment

250 participants

Start Date

Jun 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this non-interventional study is to collect data on the risk factors for acute radiation pneumonitis in patients with prior receipt of immune checkpoint inhibitors.


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is looking at why some cancer patients develop lung inflammation (called radiation pneumonitis) after receiving chest radiation therapy, specifically in people who previously received immunotherapy drugs called immune checkpoint inhibitors. **You may be eligible if...** - You have a confirmed cancer diagnosis - You previously received immunotherapy (immune checkpoint inhibitors) before chest radiation therapy - You then underwent chest radiation therapy (intensity-modulated radiotherapy) **You may NOT be eligible if...** - You did not receive immunotherapy before your chest radiation treatment - Your radiation treatment was not directed at the chest area Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONCancer patients underwent thoracic intensity-modulated radiotherapy

Cancer patients underwent thoracic intensity-modulated radiotherapy, previously received ICIs


Locations(1)

Hubei Cancer Hospital

Wuhan, Hubei, China

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NCT05219851


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