RecruitingNot ApplicableNCT05223608

Prospective Cohort With Clinic-biologic Database of Patients Treated by Immunotherapy


Sponsor

Centre Oscar Lambret

Enrollment

651 participants

Start Date

Mar 3, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

ImmuCCo-1905 is a monocentric interventional study on patients treated by immunotherapy, which consist in establishment of a prospective clinic-biologic database over 5 years, associated with a biobank. This database will allow carrying out works aiming at assessing immunotherapy in real life situation.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Age ≥ 18 years
  • Beginning a first immunotherapy by immune checkpoint inhibitor - anti-PD1 (Programmed cell Death protein-1), anti-PDL1 (Programmed cell Death protein-1 ligand), anti-CTLA4 (Cytotoxic T-Lymphocyte associated protein 4), as monotherapy or in combination, in the Centre Oscar Lambret (COL)
  • In neo-adjuvant, adjuvant, recurrence or metastatic situation
  • Suffering from solid tumor histologically documented
  • Signed written informed consent
  • Patient covered by the French " "Social Security" regime If the patient is already enrolled in clinical trial involving immunotherapy, the agreement of the sponsor of this new trial will be sought before his/her inclusion.

Exclusion Criteria4

  • Pregnant or breastfeeding women
  • Patient already treated by immunotherapy by immune checkpoint inhibitor
  • Person under guardianship
  • Inability to comply with medical follow-up of the trial (geographical, social or psychic reasons)

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Interventions

OTHERImmuCCo Cohort

Blood sampling at initiation of immunotherapy, at the first tumor assessment, in case of severe toxicity. Urine collection at initiation of immunotherapy.


Locations(1)

Centre Oscar Lambret

Lille, Hauts-de-France, France

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NCT05223608


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