RecruitingNCT05236114

GEMINI-NSCLC: NSCLC Biomarker Study

TEMPUS GEMINI NSCLC STUDY: A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Non-Small Cell Lung Cancer (NSCLC)

Sponsor

Tempus AI

Enrollment

1,200 participants

Start Date

Jun 22, 2022

Study Type

OBSERVATIONAL

Summary

GEMINI NSCLC Study is a non-interventional study that will be collecting clinical and molecular health information from patients with NSCLC who will receive longitudinal blood collection in addition to their standard of care therapy and disease surveillance with the goals of identifying the molecular evolution of lung cancer with standard of care therapy, and determining the utility of ctDNA dynamics to predict risk of recurrence and therapeutic outcomes.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This biomarker study tracks blood samples from patients with non-small cell lung cancer (NSCLC) — both early-stage (resectable) and advanced (stage IV) — to see if a blood test detecting cancer DNA can predict how well treatment is working and whether the cancer returns. **You may be eligible if...** - You have been diagnosed with NSCLC and are having or planning to have surgery (early-stage), OR you have stage IV NSCLC starting immunotherapy - You are 18 or older and willing to have additional blood draws during routine visits **You may NOT be eligible if...** - You are not willing to provide additional blood samples - Your cancer is not NSCLC (e.g., lymphoma or metastasis from another cancer) - You have had another cancer diagnosis within the last 2 years (with some exceptions) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERObservation

No intervention

Locations(58)

Alabama Oncology

Birmingham, Alabama, United States

Mercy Clinic Oncology - Fort Smith

Fort Smith, Arkansas, United States

MemorialCare

Fountain Valley, California, United States

Cancer and Blood Specialty Clinic

Los Alamitos, California, United States

UCLA

Los Angeles, California, United States

Eastern CT and Hematology and Oncology Associates

Norwich, Connecticut, United States

Clermont Oncology Center

Clermont, Florida, United States

Woodlands Medical Specialists

Pensacola, Florida, United States

Morehouse School of Medicine (MSM)

Atlanta, Georgia, United States

Piedmont Healthcare

Atlanta, Georgia, United States

Hawaii Cancer Care

Honolulu, Hawaii, United States

Southern Illinois Hospital Services

Carterville, Illinois, United States

Cancer Care Specialists of Illinois

Decatur, Illinois, United States

Northwestern University

Evanston, Illinois, United States

Hope and Healing Cancer Services

Hinsdale, Illinois, United States

OSF Saint Anthony Medical Center

Rockford, Illinois, United States

Community Health Network

Indianapolis, Indiana, United States

University of Iowa

Iowa City, Iowa, United States

University of Maryland

Baltimore, Maryland, United States

Johns Hopkins University

Baltimore, Maryland, United States

The Center for Cancer and Blood Disorder

Bethesda, Maryland, United States

Frederick Health Regional System

Frederick, Maryland, United States

Mercy Clinic Oncology and Hematology - Joplin

Joplin, Missouri, United States

Lake Regional Health System

Osage Beach, Missouri, United States

Mercy Clinic Cancer and Hematology - Chub O'Reilly Cancer Center

Springfield, Missouri, United States

Oncology Hematology Associates

Springfield, Missouri, United States

Mercy Clinic Oncology and Hematology - Sindelar Cancer Center

St Louis, Missouri, United States

Mercy Clinic Oncology and Hematology - David C. Pratt Cancer Center

St Louis, Missouri, United States

Nebraska Cancer Specialists

Omaha, Nebraska, United States

OptumCare Cancer Care

Las Vegas, Nevada, United States

Hope Cancer Care of Nevada

Las Vegas, Nevada, United States

Cancer Care Specialists Reno

Reno, Nevada, United States

New Jersey Cancer Center

Belleville, New Jersey, United States

New York Oncology Hematology

Albany, New York, United States

Hematology Oncology Associates of Central New York

East Syracuse, New York, United States

Cayuga Medical Center

Ithaca, New York, United States

Icahn School of Medicine at Mount Sinai

New York, New York, United States

White Plains Hospital

White Plains, New York, United States

UNC

Chapel Hill, North Carolina, United States

Duke University

Durham, North Carolina, United States

Southeastern Medical Oncology Center (SMOC)

Goldsboro, North Carolina, United States

Aultman Hospital

Canton, Ohio, United States

TriHealth Cancer Institute

Cincinnati, Ohio, United States

Ohio State University

Columbus, Ohio, United States

OhioHealth Reseach Institute

Columbus, Ohio, United States

Taylor Cancer Research Center

Maumee, Ohio, United States

Hightower Clinical

Oklahoma City, Oklahoma, United States

Mercy Clinic Oncology and Hematology - Coletta

Oklahoma City, Oklahoma, United States

Oklahoma Cancer Specialists and Research Institute

Tulsa, Oklahoma, United States

Oregon Oncology Specialists

Salem, Oregon, United States

Cancer Care Associates of York

York, Pennsylvania, United States

The Medical University of South Carolina

Charleston, South Carolina, United States

Baptist Cancer Center

Memphis, Tennessee, United States

University of Virginia

Charlottesville, Virginia, United States

PeaceHealth St. Joseph Medical Center-Bellingham

Bellingham, Washington, United States

Cancer Care Northwest

Spokane Valley, Washington, United States

ThedaCare Regional Cancer Center

Appleton, Wisconsin, United States

Gundersen Health System

La Crosse, Wisconsin, United States

View Full Details on ClinicalTrials.gov

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NCT05236114