Gonadotropin-releasing Hormone Agonist (GnRHa) Plus Letrozole In Young Women With Early Endometrial Cancer
Gonadotropin-releasing Hormone Agonist Combined With Letrozole Compared With Megestrol Acetate or Medroxyprogesterone Acetate Alone as Fertility-sparing Treatment in Early Endometrial Cancer
Fudan University
104 participants
Mar 11, 2022
INTERVENTIONAL
Conditions
Summary
To see if Gonadotropin-releasing hormone analogue (GnRHa) combined with aromatase inhibitors (AIs) will achieve better complete response rate than megestrol acetate or medroxyprogesterone acetate (MA/MPA) alone as fertility-sparing treatment for patients with early endometrial carcinoma.
Eligibility
Plain Language Summary
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Interventions
At a dosage of 160 mg/day
At a dosage of 500 mg/day
Intramuscular injection of 3.75mg was given 4 weeks apart and the maximum use are 6 courses
At a dosage of 2.5mg/day and no more than 24 weeks
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05247268