RecruitingNCT05253560

Prodromal Parkinsonian Features in GBA1 Mutation Carriers


Sponsor

Shaare Zedek Medical Center

Enrollment

600 participants

Start Date

May 16, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

Objective of the trial. To define a sub-population which is at increased risk of developing Parkinson, beyond the fact of carrying Gaucher; in this sub-population the investigators shall conduct a comprehensive evaluation that includes a variety of non-invasive tests, whose purpose is to evaluate the state of the pre- Parkinson's disease signs, signs which can appear, even twenty years before the appearance of the disease, and also to compare them to a group of diagnosed Gaucher patients and a group of healthy people who are not carriers of Gaucher disease. A group of those carriers will be available for trial or for treatment, if there will be a medicine for the prevention of the development of Parkinson, obtainable.


Eligibility

Min Age: 40 YearsMax Age: 75 Years

Inclusion Criteria1

  • Willing to participate

Exclusion Criteria2

  • PD patients
  • Dementia

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Interventions

DIAGNOSTIC_TESTThe investigators aim to identify prodromal PD in a cohort of carriers of Gaucher disease.

Tests to help identify prodromal PD in a cohort of carriers of Gaucher disease


Locations(1)

Michal Becker- Cohen

Jerusalem, Please Select..., Israel

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NCT05253560


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