RecruitingNot ApplicableNCT05255289

Efficacy/Safety of Midurethral Sling

Evaluation of Efficacy and Safety of Midurethral Slings in Women With Stress Incontinence


Sponsor

Mackay Medical College

Enrollment

200 participants

Start Date

Mar 8, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The trans-obturator tape (TOT), which exhibits a satisfactory cure rate and a relatively diminished invasiveness, has been increasingly accepted as a surgical treatment of stress urinary incontinence (SUI) patients. Nevertheless, in contrast to the well-recognized therapeutic benefit of the enhanced resistance to the bladder continence during urine storage, if the voiding function of the bladder adapts to the TOT-enhanced outlet resistance has not been adequately investigated. This study retrospectively assayed the voiding efficacy of each voiding cycle, to clarify if the thermodynamic efficacy of the bladder was modified in response to the TOT surgery.


Eligibility

Sex: FEMALEMin Age: 30 YearsMax Age: 100 Years

Inclusion Criteria2

  • Clinical diagnosis of stress urinary incontience
  • Have urodynamic investigations before and after operation.

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Interventions

PROCEDUREUrodynamic investigations before and after a trans-obturator tape protocol.

Urodynamic investigations (The urodynamic study included free uroflowmetry, postvoid residual, filling and voiding cystometry, and a urethral pressure profile. The filling cystometry and urethral pressure profile were performed with 37 degrees C normal saline similar to body temperature at an infusion rate of 80 ml/min.)

PROCEDUREUrodynamic investigations before and after a tension-free vaginal tape-obturator (TVT-O)

Urodynamic investigations (stated above.)

PROCEDUREUrodynamic investigations before and after a mini Arc protocol.

Urodynamic investigations (stated above)

PROCEDUREUrodynamic investigations before and after an i-STOP mini adjustable sling protocol.

Urodynamic investigations (stated above)

PROCEDUREUrodynamic investigations before and after an Solyx sling protocol.

Urodynamic investigations (stated above.)


Locations(1)

Department of Obstetrics and Gynecology

New Taipei City, Taiwan

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NCT05255289


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