Inter-lobar Fissure Completion in Patients With Failed Bronchoscopic Lung Volume Reduction

This study is testing a surgical procedure to help people with severe emphysema who did not benefit enough from a previous lung treatment called bronchoscopic lung volume reduction (BLVR). The surgery completes an incomplete fissure (a natural dividing line) in the lung to help the one-way valves already placed work better and reduce lung overinflation. **You may be eligible if...** - You are between 40 and 75 years old - You still have the endobronchial valves (placed during your previous BLVR procedure) in place - You are still very short of breath after your BLVR procedure - Your previous BLVR reduced lung volume by less than 350 ml - You have not smoked for at least 4 months and are willing to stay smoke-free during the study - You are up to date on your pneumococcal and influenza vaccinations **You may NOT be eligible if...** - You had a heart attack within the last 6 months - You have severe heart failure or uncontrolled heart disease - You produce large amounts of mucus daily - You have had previous lung surgery in the target area Talk to your doctor to see if this trial is right for you.