RecruitingNot ApplicableNCT05268341

Neuroimaging Reveals Treatment-related Changes in DLD


Sponsor

University of Cincinnati

Enrollment

184 participants

Start Date

May 24, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Children with developmental language disorders (DLD, aka specific language impairment), a prevalent pediatric disorder, experience hallmark grammar deficits with life-long impacts on educational and occupational outcomes. While effective and early interventions can mitigate the impact of DLD, not enough is known about the neural basis of DLD in young children, yet is needed to inform the design of more individualized interventions. This project uses neuroimaging, along with behavioral methods, with the goal of better understanding the memory-language mechanisms that underlie grammar learning and impairment, while also considering their association to treatment-related changes in preschoolers with DLD.


Eligibility

Min Age: 48 MonthsMax Age: 71 Months

Inclusion Criteria10

  • ages 48-71 months
  • average nonverbal intelligence quotient (IQ)
  • enrolled in participating center
  • typically developing (receptive and expressive language, social, articulation, other)
  • DLD for expressive grammar
  • typical oral motor function
  • typical social/pragmatics skills
  • average hearing thresholds
  • monolingual and native Standard English speakers
  • does not have any uncorrected vision challenges

Exclusion Criteria3

  • receiving co-occurring speech-language or other intervention for communication
  • not MRI safe
  • special education placement of child based on ability or behavior

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Interventions

BEHAVIORALMy Sentence Builder

computer-assisted treatment program for expressive grammar


Locations(6)

New Horizon Childcare

Cincinati, Ohio, United States

Empower Learn Create INC

Cincinnati, Ohio, United States

Cincinnati Children's Hospital

Cincinnati, Ohio, United States

CWFF CHild Development Center

Cincinnati, Ohio, United States

Wesley Education Center for Children and Families

Cincinnati, Ohio, United States

University of Cincinnati

Cincinnati, Ohio, United States

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NCT05268341


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