RecruitingNCT05277519

Neuroplasticity After Proprioceptive Rehabiliation

Neuroplasticity Induced by Functional Muscle Tendon Vibrations in Patients With Acquired Brain Injury


Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

56 participants

Start Date

Jun 16, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Sequences of muscle tendon vibrations allow to reproduce the sensory feedback during movement like locomotion and kinaesthesia. It is known that such a treatment promotes motor recovery after stroke assuming that it enhances neuroplasticity. The aim of the research is to study the activity in cerebrospinal circuitry to evaluate the neuroplastic changes during and after instrumented proprioceptive rehabilitation relying on sequences of muscle vibration in subacute stroke stages.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria8

  • hemiparesis at least transient in lower limb following an acquired brain injury (stroke or traumatic brain injury)
  • French spoken
  • Affiliated to a French social insurance
  • No previous traumatic, vascular or neurodegenerative injuries
  • Having presented during the acute phase or presenting a motor deficit of one of the lower limbs
  • Presenting an absence of autonomy of walking at the entrance of the rehabilitation department
  • In the sub-acute phase, i.e. from 15 days to 6 months after the accident
  • Presenting moderate cognitive disorders allowing them to understand instructions and give their consent

Exclusion Criteria4

  • strong cognitive disorders
  • maintenance of justice, tutelage, legal guardianship
  • Pregnancy and breastfeeding
  • Outpatients who do not have weekly follow-up in the rehabilitation department

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Interventions

DEVICEVibrations

Sequenced muscle vibrations during 30 min., 3 times a week during 5 weeks


Locations(1)

Pitié-Salpêtrière Hospital

Paris, France

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NCT05277519


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