Adjuvant Concurrent Chemoradiotherapy Versus Radiotherapy in Early-stage Cervical Cancer Patients

This study compares radiation alone versus radiation combined with chemotherapy (concurrent chemoradiotherapy) for early-stage cervical cancer patients who have had a hysterectomy and have specific risk factors for recurrence. **You may be eligible if...** - You are 18–80 years old with confirmed cervical cancer (FIGO stage Ia2–IIb) - You had a radical hysterectomy 3–4 weeks before starting the study - Your post-surgery pathology shows specific intermediate-risk features (e.g., lymphovascular invasion with deep tumor invasion, large tumor size, or non-squamous cell type) - Your performance score is 70 or above (Karnofsky) - You have not received prior chemotherapy or radiation **You may NOT be eligible if...** - You have cancer remaining after surgery, or evidence of spread (lymph nodes, margins, or parametrial invasion) - You had pelvic or aortic lymph node metastases found at surgery - Your pathology showed positive surgical margins - You are not fit for radiation or chemotherapy Talk to your doctor to see if this trial is right for you.