RecruitingNCT05280028

HRT on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial Stiffness

The Impact of Different Hormone Therapy Regimens on Overactive Bladder Symptoms, Sexual Function, Depressive Symptoms, Autonomic Function, and Arterial Stiffness


Sponsor

Far Eastern Memorial Hospital

Enrollment

100 participants

Start Date

Feb 7, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Therefore, the aim of this study is to assess the therapeutic effect on overactive bladder symptoms, sexual function, heart rate variability, arterial stiffness, atherosclerosis, sleep, and depression between tibolone and E2V/MPA. From the results, the investigators will compare the effect of tibolone versus E2V/MPA on overactive bladder symptoms, sexual function, autonomic function, arterial stiffness, atherosclerosis, sleep and depression.


Eligibility

Sex: FEMALEMin Age: 20 Years

Inclusion Criteria2

  • \>20 years old female
  • Menopausal symptoms, still have a uterus, and no breast or other cancers, and no vascular-blocking disease such as stroke.

Exclusion Criteria1

  • Nil.

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Interventions

DRUGTibolone 2.5 mg

Tibolone 2.5 mg per day

DRUGEstradiol valerate 1 mg/medroxyprogesterone acetate 2.5 mg

Estradiol valerate 1 mg/medroxyprogesterone acetate 2.5 mg per day


Locations(1)

Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital

Banqiao District, New Taipei, Taiwan

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NCT05280028


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