Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma

This study tests a drug called orellanine in people with advanced kidney cancer (clear cell or papillary renal cell carcinoma) for whom no other standard treatments are available or appropriate. **You may be eligible if...** - You are 18 or older - You have been diagnosed with advanced kidney cancer (clear cell or papillary type) confirmed by biopsy - No standard treatments are available, suitable, or you have chosen to decline them - Your overall health is reasonably good (able to care for yourself) - You have a life expectancy of at least 3 months - Your blood counts, liver function, and other lab results are within acceptable ranges **You may NOT be eligible if...** - Your kidney cancer has not been confirmed by a biopsy - You are in poor general health - Your lab results show significant problems with blood counts or organ function - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.