Ovarian Tissue Cryopreservation in Pre-Pubertal (OTC-Pre Pubertal)

This study offers ovarian tissue freezing (cryopreservation) to pre-pubertal children facing treatments that could harm their fertility. Part of the ovary is removed and frozen so that it may be reimplanted later in life to preserve the ability to have children and natural hormones. **You may be eligible if...** - You are a pre-pubertal child (before puberty begins) - You are about to undergo surgery, chemotherapy, or radiation that is likely to harm your fertility, such as: removal of an ovary, heavy pelvic radiation, or high-dose chemotherapy drugs (like cyclophosphamide, busulfan, or procarbazine) **You may NOT be eligible if...** - You do not meet the specific treatment intensity thresholds - Other medical conditions make surgery unsafe Talk to your doctor to see if this trial is right for you.