Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma

This trial tests an adaptive radiation therapy approach called HEAT (Habitat Escalated Adaptive Therapy) for soft tissue sarcoma (cancer of muscles, fat, or connective tissue) before surgery. By targeting the most aggressive areas of the tumor with higher radiation doses, the aim is to improve tumor shrinkage. **You may be eligible if...** - You have been diagnosed with soft tissue sarcoma and are scheduled for radiation before surgery - You are willing to use effective contraception during and for 52 weeks after radiation (if applicable) - You can commit to the study schedule and lifestyle guidelines **You may NOT be eligible if...** - You are pregnant or planning to become pregnant during the study - You cannot attend the required treatment sessions Talk to your doctor to see if this trial is right for you.