Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome
Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome : a Monocentric Pilot Study
Central Hospital, Nancy, France
10 participants
Dec 9, 2022
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to assess the drug absorption of oral antibiotics in patients with short bowel syndrome.
Eligibility
Inclusion Criteria6
- Short bowel syndrome
- Treated for a documented infection with antibiogram by amoxicillin (+/- clavulanic acid)or ofloxacin or levofloxacin or sulfamethoxazole/trimethoprim
- Hospitalized in the Nutritional Assistant Unit or the Infectiology Unit of the Regional University Hospital of Nancy
- Affiliated to a social security system
- Having received an physical examination before entering study
- Having received full information regarding the study organization and having signed the informed consent
Exclusion Criteria6
- Patient at risk of worsening their oral absorption abilities during study
- Patient requiring dialysis
- Women of childbearing age without efficient birth control
- Allergy to any of the drugs tested
- Person concerned by Articles L. 1121-5, L. 1121-7 et L1121-8 of the Code of public health
- Person deprived of liberty or person undergoing psychiatric care pursuant to articles L. 3212-1 et L. 3213-1
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Each patient will receive the proper antibiotic to treat the infection, first intravenously, then orally
Each patient will receive the proper antibiotic to treat the infection, first intravenously, then orally
Each patient will receive the proper antibiotic to treat the infection, first intravenously, then orally
Each patient will receive the proper antibiotic to treat the infection, first intravenously, then orally
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05302531