RecruitingNCT05304858

Tumor Microenvironment Analysis of Prostate Cancer Metastasis

Connecting Lineage Target Expression and Immune Tumor Microenvironment Analysis of Prostate Cancer Metastasis


Sponsor

Columbia University

Enrollment

16 participants

Start Date

Sep 15, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to collect prostate cancer tissue from males with metastatic prostate cancers in order to study the tumor microenvironment (TME), which is the area surrounding the tumor including cells, blood vessels, etc., in men with metastatic prostate cancer. The type of research performed on these tissue samples include genetic \& molecular analyses.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study collects tumor tissue samples from men with prostate cancer that has spread (metastatic), specifically to analyze the environment surrounding the cancer cells (tumor microenvironment). The goal is to understand why some prostate cancers spread and how the immune system responds. **You may be eligible if...** - You are 18 or older with a confirmed prostate cancer diagnosis - Your cancer has spread to other parts of the body (metastatic) - You have reasonable physical function (ECOG 0–2) - You are willing to have a biopsy of a metastatic tumor **You may NOT be eligible if...** - You are unable to safely undergo a biopsy procedure - You are not willing to provide informed consent - You do not meet the physical function or other eligibility criteria Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiopsy

Standard of care surgical procedures to collect prostate cancer tissue from men with metastatic prostate cancers. Non-experimental.


Locations(1)

Columbia University Irving Medical Center

New York, New York, United States

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NCT05304858


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