RecruitingPhase 4NCT05309460
Labetalol or Nifedipine for Control of Postpartum Hypertension: A Randomized Controlled Trial
Sponsor
Nebraska Methodist Health System
Enrollment
600 participants
Start Date
Jun 20, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
Randomized trial comparing risk of hospital readmission and hypertensive complications between patients managed on Labetalol compared to Nifedipine.
Eligibility
Sex: FEMALEMin Age: 19 Years
Plain Language Summary
Simplified for easier understanding
This study compares two blood pressure medications — labetalol and nifedipine — to find out which is safer and more effective for controlling high blood pressure after childbirth (postpartum hypertension). High blood pressure after delivery is a serious but common complication.
**You may be eligible if...**
- You delivered a baby (vaginally or by C-section) at 24 weeks of pregnancy or later
- You have high blood pressure after delivery (systolic ≥140 mmHg or diastolic ≥90 mmHg on two separate readings)
- You speak English or Spanish
**You may NOT be eligible if...**
- You have moderate or severe persistent asthma, coronary artery disease, heart failure, a heart block, or fluid in the lungs (pulmonary edema)
- You have a medical reason you cannot take either nifedipine or labetalol
- Your heart rate is below 60 or above 110 beats per minute
- Your primary language is not English or Spanish
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGLabetalol Oral Tablet
See Labetalol arm.
DRUGNIFEdipine ER
See Nifedipine arm.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05309460
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