RecruitingNot ApplicableNCT05318274

Hypofractionated Radiation Therapy vs Standard Treatment in Breast Cancer.

Hypofractionated Radiation Therapy (1 Week) Compared With Standard Treatment (3.1 Weeks), Evaluation of Local Control of Breast Cancer Treated With Conservative Surgery.


Sponsor

Coordinación de Investigación en Salud, Mexico

Enrollment

72 participants

Start Date

Apr 26, 2021

Study Type

INTERVENTIONAL

Summary

An explanatory study comparing complementary treatment to breast conservative surgery with radiation therapy DCIS, T1-T2 N0 M0 (AJCC v8) 1 week schedule vs 3.1 weeks standard schedule, in order to determine the equivalence of local tumor control, survival, acute and chronic toxicity. Shorter curse of radiation therapy may lead to similar local control of tumor cells and lower rates of toxicity than 3.1 standard treatment.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study compares a shorter, higher-dose radiation schedule (hypofractionated) to the standard longer radiation schedule for breast cancer patients who had breast-conserving surgery (a lumpectomy). **You may be eligible if...** - You have been diagnosed with early-stage breast cancer (DCIS or invasive) confirmed by biopsy - You had a lumpectomy (breast-conserving surgery) - Your cancer is stage pT1-T2, no lymph node spread, no distant spread - You are 18 or older **You may NOT be eligible if...** - Cancer has spread to your lymph nodes - Your tumor is large (stage T3 or T4) - You have had radiation to the same area before - Your surgical margins were not clear (positive margins after surgery) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONHypofractionated radiotherapy

Ultra hypofractionated 26 Gy in 5 fractions applied once with daily port film.


Locations(1)

Unidad Medica de Alta Especialidad

Mérida, Yucatán, Mexico

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NCT05318274