Trial of Brexpiprazole Once-weekly (QW) Formulation in Patients With Acute Schizophrenia

This study tests a once-weekly injectable formulation of brexpiprazole — a medication used to treat schizophrenia and as an add-on for depression — to evaluate if the long-acting version is as effective and safe as daily oral doses. **You may be eligible if...** - You have schizophrenia or major depressive disorder being treated with brexpiprazole - You are currently stable on daily oral brexpiprazole - You are 18 or older - You consent to switch to the weekly injection formulation **You may NOT be eligible if...** - You have a history of non-adherence that cannot be managed - You are pregnant or planning pregnancy - You have severe liver disease - You have had a recent hospitalization for psychiatric crisis Talk to your doctor to see if this trial is right for you.