RecruitingNCT05325736

Improvement in Glycemic Response After Bariatric Surgery


Sponsor

Weizmann Institute of Science

Enrollment

120 participants

Start Date

Jul 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

decipher the role of microbiota in glycemic response change after bariatric surgery


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

  • candidates of bariatric surgery or cholecystectomy
  • age 18-70
  • male/female

Exclusion Criteria7

  • previous bariatric surgery
  • type 1 diabetes
  • antibiotic treatment 3 months prior to the study
  • probiotic treatment 3 months prior to the study
  • chronic disease - gastrointestinal disease, malignancy, psychiatric disorder, endocrinologic disorders
  • any pathologic findings during endoscopy
  • participants who will suffer from a post-operation complication

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Interventions

PROCEDUREsleeve gastrectomy surgery

participants undergoing sleeve gastrectomy surgery

PROCEDUREgastric bypass surgery

participants undergoing gastric bypass surgery

PROCEDUREcontrol

cholecystectomy

PROCEDUREPancreatectomy

Collecting a sample of an unidentified healthy pancreas to extract insulin-secreting beta cells from the sample


Locations(2)

Weizmann Institute of Science

Rehovot, Israel

Souraski medical center

Tel Aviv, Israel

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NCT05325736


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