RecruitingNCT05326828

Implantable Cardiac Monitor to Detect Atrial Fibrillation in Patients With MINOCA

Sponsor

Insel Gruppe AG, University Hospital Bern

Enrollment

60 participants

Start Date

May 24, 2022

Study Type

OBSERVATIONAL

Conditions

Atrial Fibrillation MINOCA

Summary

Myocardial infarction with non-obstructive coronary arteries (MINOCA) (i.e.\<50% stenoses) on coronary angiography) is an underappreciated clinical entity concerning 5-6% of patients with acute myocardial infarction. Approximately 50% of these patients remain without appropriate diagnosis and treatment. The MINOCA study aims at systematically assessing the frequency of underlying pathologies of MINOCA and outcomes with a multidisciplinary etiologic work-up and follow-up of 5 years including, for the first time, an implantable cardiac monitor (ICM) to assess the frequency of atrial fibrillation as underlying cause for MINOCA.

Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether a small heart monitor implanted under the skin can detect an irregular heart rhythm (atrial fibrillation) in patients who had a heart attack with no blocked arteries — a condition called MINOCA. **You may be eligible if...** - You are 18 or older - You had a heart attack (type 1) but your coronary arteries were not significantly blocked - Cardiac MRI showed injury consistent with a heart attack - No clear cause for your heart attack was found **You may NOT be eligible if...** - You already have a known history of atrial fibrillation or flutter - You have had a previous heart attack or coronary artery disease - You have had coronary bypass surgery or a stent placed - You have kidney disease with severely reduced function - A clear cause for your MINOCA was already found Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICECONFIRM Rx implantable cardiac rhythm monitor (Abbott)

Implantation of CONFIRM Rx ICM

DIAGNOSTIC_TESTSystematic etiologic work-up for underlying causes of MINOCA

Intracoronary optical coherence tomography, cardiac magnetic resonance imaging, transesophageal echocardiography, vasospasm testing, thrombophilia screening, Holter ECG (only non-ICM group)