RecruitingNot ApplicableNCT05327465

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy: POWER Trial


Sponsor

Dana-Farber Cancer Institute

Enrollment

62 participants

Start Date

Aug 11, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to determine whether a 16-week culturally tailored, technology-based, aerobic and resistance exercise intervention improves cardiovascular risk factors in Black men diagnosed with prostate cancer and are undergoing androgen deprivation therapy (ADT), and whether it will also improve physical fitness and function, body composition, and outcomes such as quality of life, cancer symptoms, and self-esteem. Participants in this study will be randomly assigned to one of two groups: 1) Aerobic and resistance exercise, or 2) Usual care.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether an exercise program can improve heart health in Black men with prostate cancer who are receiving hormone-suppressing therapy (androgen deprivation therapy, or ADT), which is known to negatively affect the cardiovascular system. **You may be eligible if...** - You are over 18 and self-identify as Black - You have been diagnosed with prostate cancer and have been on ADT for at least one month - You plan to continue ADT for at least 4 more months - You are cleared by your doctor to exercise - You currently exercise less than 60 minutes per week (moderate or vigorous) - You speak English or Spanish and can travel to Dana-Farber Cancer Institute **You may NOT be eligible if...** - You are not currently receiving ADT - You have uncontrolled heart, lung, or metabolic disease - You already exercise more than 60 minutes per week - You have another active cancer diagnosis Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAerobic and resistance exercise

Perform exercise at home with virtual supervision, including aerobic exercise (e.g.,cycling), which can improve cardiovascular (heart) and lung function, and resistance exercise (e.g., dumbbell lifting and using resistance band. The exercises will be performed three times per week for 16 weeks, and virtually supervised by a professional exercise trainer

OTHERUsual Care

Maintenance of baseline exercise levels for 16 weeks with an offer to perform the same exercise (aerobic and resistance exercise) program after 16 weeks.


Locations(1)

Dana Farber Cancer Institute

Boston, Massachusetts, United States

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NCT05327465


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