RecruitingPhase 4NCT05331664

Dropless Pars Plana Vitrectomy Study

Sponsor

Massachusetts Eye and Ear Infirmary

Enrollment

168 participants

Start Date

Jul 25, 2022

Study Type

INTERVENTIONAL

Conditions

rhegmatogenous retinal detachment

Summary

To demonstrate that intraoperative use of subtenon triamcinolone acetonide at the time of surgery without postoperative eye drops is non-inferior to the regimen of postoperative eye drops following primary pars plana vitrectomy for retinal detachment.

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Atropine 1%, a drug called Moxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin, and others for people with rhegmatogenous retinal detachment. The study is currently recruiting participants at 1 location. People eligible for this study include aged 40 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPars plana vitrectomy

Standard of care surgery

DRUGTriamcinolone Acetonide 40mg/mL

Sub-tenon injection of triamcinolone acetonide (40mg/mL) at the time of surgery

DRUGMoxifloxacin 0.5% or Polymyxin/Trimethoprim if patient is allergic to moxifloxacin

Antibiotic eye drop 4 times per day for 1 week after surgery

DRUGPrednisolone 1%

Steroid eye drop 4 times per day tapered by one drop weekly for 4 weeks (4/3/2/1 taper) after surgery

DRUGAtropine 1%

Eye drop daily for 1 week after surgery

Locations(1)

Massachusetts Eye and Ear

Boston, Massachusetts, United States

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NCT05331664

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