Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane on Long-term Outcomes With Patients Undergoing Elective Excision of Primary Liver Tumors
Impact of Propofol-Based Total Intravenous Anesthesia Versus Anesthesia With Sevoflurane
Kaohsiung Medical University Chung-Ho Memorial Hospital
500 participants
Apr 26, 2022
INTERVENTIONAL
Conditions
Summary
This is a two-arm, parallel-group randomized clinical trial. Routine perioperative care would be performed in volunteers with primary Hepatocellular carcinoma. The study will enroll approximately 500 volunteers to compare the progression-free or overall survival in patients undergoing elective partial hepatectomy for primary liver tumors between propofol and sevoflurane for the maintenance of anesthesia.
Eligibility
Plain Language Summary
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Interventions
total intravenous anesthesia with propofol for the partial hepatectomy of hepatocellular carcinoma.
The sevoflurane group was maintained via sevoflurane vaporizer between 1% and 3% (target minimum alveolar concentration of 0.7-1.3 MAC).
Locations(1)
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NCT05331911