RecruitingPhase 3NCT05331937

TMS for Exposure Therapy Resistant OCD

Transcranial Magnetic Stimulation (TMS) for Patients With Exposure Therapy-resistant Obsessive-compulsive Disorder (OCD): TETRO - a Multicenter Randomized Controlled Trial


Sponsor

Amsterdam UMC, location VUmc

Enrollment

250 participants

Start Date

May 16, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

TETRO is a multi-center placebo-controlled double-blind randomized controlled trial with an intervention phase of 5-7 weeks and a follow-up phase of 12 months in 250 adult (18 years and older) OCD patients who show no/insufficient response to ERP, aiming to establish the cost-effectiveness of low frequency (1 Hz) rTMS to the pre-SMA (compared to sham rTMS to the pre-SMA) as adjuvant treatment to exposure with response prevention (ERP). The treatment consists of 4 times/week rTMS combined with ERP for at least 5 weeks (20 sessions), with optional extension phase of 1 or 2 weeks (maximum of 28 sessions in total).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying repetitive transcranial magnetic stimulation (rTMS) for people with 1 hz real rtms to the pre-sma and 1 hz sham rtms to the pre-sma. The study is currently recruiting participants at 8 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

COMBINATION_PRODUCTrepetitive transcranial magnetic stimulation (rTMS)

rTMS (real versus sham) is used as adjuvant to ERP


Locations(8)

Amsterdam UMC, location VU Medical Center

Amsterdam, North Holland, Netherlands

GGZ inGeest

Amsterdam, Netherlands

Neurocare

Eindhoven, Netherlands

Neurocare

Groningen, Netherlands

Maastricht UMC+

Maastricht, Netherlands

Mondriaan

Maastricht, Netherlands

ProPersona

Nijmegen, Netherlands

Radboudumc

Nijmegen, Netherlands

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05331937