RecruitingNot ApplicableNCT05343130

Efficacy of a Brain-Computer Interface Controlled Functional Electrical Stimulation Therapy for Spinal Cord Injury Neurorehabilitation

Efficacy of a Therapy With Brain-Computer Interface Controlled Functional Electrical Stimulation for Neurorehabilitation of Patients With Spinal Cord Injury (Eficacia de Una Terapia Con estimulación eléctrica Funcional Controlada Con Interfaz Cerebro-computadora Para neurorrehabilitación de Pacientes Con lesión Medular)


Sponsor

Instituto Nacional de Rehabilitacion

Enrollment

32 participants

Start Date

Aug 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The study's main goal is to determine the efficacy of a therapy with brain-computer interface controlled functional electrical stimulation for neurorehabilitation of spinal cord injury patients' upper limbs. For this purpose, a randomized controlled trial will be performed to compare the clinical and physiological effects of the brain-computer interface therapy with those of a sham intervention comprised by the application of functional electrical stimulation independently of brain-computer interface control.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Spinal Cord Injury at neurological levels C6 or C7
  • American Spinal Injury Association (ASIA) classification A, B, C or D
  • Upper limb spasticity of less or equal to +1 measured with the Modified Ashworth Scale
  • Time since disease onset of more than 6 months and less than 60 months
  • Normal or corrected to normal vision

Exclusion Criteria9

  • Severe attention deficits
  • Previous diagnosis of traumatic brain injury
  • Previous diagnosis of peripheral nerve injury
  • Previous stroke diagnosis
  • Previous diagnosis of neurodegenerative diseases
  • History of fractures in upper extremities
  • Skin lesions
  • Contractures in upper extremities that hamper mobility
  • Excessive muscle spasms

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Interventions

DEVICEBrain-Computer Interface

Hand movement will be elicited using functional electrical stimulation activated by the brain-computer interface based on hand movement intention.

DEVICESham Brain-Computer Interface

Hand movement will be elicited using functional electrical stimulation which activation will be independent of the brain-computer interface based on hand movement intention.


Locations(1)

Instituto Nacional de Rehabilitacion Luis Guillermo Ibarra Ibarra (National Institute of Rehabilitation)

Tlalpan, Mexico City, Mexico

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NCT05343130


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