RecruitingNCT05347732

Predictors of Failed Thrombolysis in Acute Myocardial Infarction

Predictors of Failed Thrombolysis in Acute ST-segment Elevation Myocardial Infarction


Sponsor

Oslo University Hospital

Enrollment

200 participants

Start Date

Apr 25, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this observational study is to assess why thrombolytic treatment with tissue-plasminogen activator (t-PA) fails in patients with acute ST-segment elevation myocardial infarction (STEMI). The study will include 200 STEMI patients at the time of arrival at Oslo University Hospital Ullevål after receiving prehospital thrombolysis. A blood sample will be taken immediately for the study of factors related to coagulation, fibrinolysis and inflammation. Levels of the biomarkers will be compared between patients with successful and failed thrombolysis.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • STEMI patients > 18 years given prehospital thrombolysis.

Exclusion Criteria1

  • None.

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Interventions

DIAGNOSTIC_TESTSuccessfull thrombolysis

Biomarker levels will be compared between patients with successful and failed thrombolysis.


Locations(1)

Oslo University Hospital

Oslo, Norway

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NCT05347732


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