RecruitingNot ApplicableNCT05351242

Thermotherapy Against Persistent Bacterial LUNG Infections


Sponsor

Chronic Obstructive Pulmonary Disease Trial Network, Denmark

Enrollment

150 participants

Start Date

Jan 31, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to determine whether an intervention with frequent thermotherapy will be able to reduce the amount of colonizing bacteria in the bronchoalveolar lavage sample and eradicate the colonizing bacteria.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether regular sauna use (heat therapy) can help reduce or clear persistent bacterial lung infections in people with chronic lung conditions. Participants will either go to a sauna four times per week for six months or avoid saunas completely during the same period. **You may be eligible if...** - You are 18 or older - You have had at least two positive cultures for specific lung bacteria (such as Pseudomonas aeruginosa or Staphylococcus aureus) in the last 24 months, including at least one positive culture after antibiotic treatment - Your breathing capacity (FEV1) is greater than 1.0 liters - You are willing to either attend a sauna regularly or completely avoid saunas for six months **You may NOT be eligible if...** - You are allergic to lidocaine or midazolam (used during the study bronchoscopy) - You have a condition that prevents bronchoscopy (a procedure to look into the lungs) - You have had a serious past episode of severe throat spasm requiring intubation - You are pregnant or breastfeeding - You have severe uncontrolled mental illness Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERThermotherapy/sauna bath

Thermotherapy/sauna bath


Locations(1)

Herlev and Gentofte University hospital

Hellerup, Capital Region, Denmark

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NCT05351242


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