Adaptive Optics Imaging of Outer Retinal Diseases

This study is using a highly advanced imaging technology called Adaptive Optics (AO) to take extremely detailed pictures of the retina (the back of the eye) in patients with outer retinal diseases — conditions affecting the light-sensitive layers of the eye. The goal is to better understand how these conditions affect retinal cells over time. You may be eligible if... - You are 21 years old or older - You have been diagnosed with an outer retinal disease or condition - You are able to follow instructions and sit still for an eye exam - You can read and sign an informed consent in English You may NOT be eligible if... - You have unstable eye fixation or media opacity that prevents good images - Your vision correction (glasses prescription) is outside the range of +4 to -8 diopters - You have had a bad reaction to eye-dilating drops before - You have a history of acute angle-closure glaucoma or a predisposition to it - You work directly under the study investigators at NIH/NEI Talk to your doctor to see if this trial is right for you.