RecruitingNot ApplicableNCT05356117

Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

Resistance Exercise Combined With Protein Supplementation for Skeletal Muscle Mass in People With Pancreatic Cancer Undergoing Chemotherapy: The RE-BUILD Trial


Sponsor

Dana-Farber Cancer Institute

Enrollment

45 participants

Start Date

Sep 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this research is to determine whether a virtually supervised resistance exercise (RE) intervention combined with protein supplementation (PS) is feasible in pancreatic cancer patients initiating chemotherapy and if it will improve skeletal muscle mass. The names of the study interventions involved in this study are: * Resistance training and protein supplement intake (RE + PS) * Resistance training (RE) * Attention control (AC), home-based stretching


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (called RE-BUILD) is testing whether a structured resistance exercise program combined with protein supplements can help people with pancreatic cancer maintain muscle mass and strength while they are receiving chemotherapy before surgery (neoadjuvant chemotherapy). **You may be eligible if...** - You have non-metastatic pancreatic cancer and are starting pre-surgery chemotherapy - You are 18 or older and can speak English or Spanish - You are currently doing 60 minutes or less of structured exercise per week - You have your doctor's clearance to exercise - You are a non-smoker and are able to travel to the study center **You may NOT be eligible if...** - You have another active cancer - You have a metastatic disease - You have uncontrolled medical conditions such as infections, uncontrolled diabetes, or hypertension - You have a history of conditions that prevent safe exercise (e.g., serious heart, lung, or nerve/muscle disorders) - You are currently pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALResistance Training (RT) and Protein Supplementation (PS)

Aerobic and resistance exercise with orally consumed pre-packed protein supplement

BEHAVIORALResistance Training (RT)

Aerobic and resistance exercise

BEHAVIORALAttention Control (AC

Stretching


Locations(1)

Dana Farber Cancer Institute

Boston, Massachusetts, United States

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NCT05356117


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