RecruitingNot ApplicableNCT05356286

Recording of Intraoperative Spinal Cord Stimulation and Monitoring


Sponsor

University of California, Los Angeles

Enrollment

150 participants

Start Date

Jan 21, 2011

Study Type

INTERVENTIONAL

Conditions

Summary

Opioid overdose suppresses brainstem respiratory circuits, causes apnea, and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid-induced respiratory depression in humans. In this study, we will stimulate the spinal cord during surgery and assess its effects on respiratory function in human patients.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a medical device called epidural electrical stimulation for people with cervical stenosis, disk, herniated, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEepidural electrical stimulation

Electrical spinal cord stimulation will be used to modulate respiratory function during general anesthesia.


Locations(1)

University of California, Los Angeles

Los Angeles, California, United States

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NCT05356286


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