RecruitingPhase 2Phase 3NCT05357690

A Study of Stellate Ganglion Block for Prevention of Atrial Fibrillation

Stellate Ganglion Blockade for the Prevention of Atrial Fibrillation After Cardiac Surgery: A Randomized Placebo-Controlled Trial

Sponsor

Mayo Clinic

Enrollment

220 participants

Start Date

Apr 19, 2023

Study Type

INTERVENTIONAL

Conditions

Atrial Fibrillation

Summary

The purpose of this study is to test if a nerve block procedure called a stellate ganglion block can help decrease the chance of atrial fibrillation after surgery. Atrial fibrillation is the abnormal, fast beating of the upper chambers of the heart. Stellate ganglion blockade has shown to decrease other types of abnormal heart rhythms as well as decrease the chance of atrial fibrillation.

Eligibility

Min Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a nerve block procedure called a stellate ganglion block — a targeted injection near the neck — can reduce the risk of developing an irregular heartbeat (atrial fibrillation) after open heart surgery. **You may be eligible if...** - You are scheduled for mitral or aortic valve surgery at Mayo Clinic in Rochester, Minnesota - Your surgery may or may not include coronary artery bypass grafting (CABG) **You may NOT be eligible if...** - You already have permanent atrial fibrillation - You are having a ventricular assist device implanted or removed - Your surgery does not require a heart-lung bypass machine - Your surgery requires deep hypothermic circulatory arrest (a technique used in complex aortic repairs) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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