RecruitingNCT05362370

Stryker PEEK Customized Implant: A Prospective Post Market Follow Up to Evaluate Safety, Performance and Effectiveness


Sponsor

Stryker Craniomaxillofacial

Enrollment

110 participants

Start Date

Feb 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to confirm the safety, performance and effectiveness of Stryker's PEEK Customized Implants when used for the augmentation and/or restoration of bony and/or soft tissue deformities in the cranial and craniofacial skeleton. The study is designed as a prospective, multi-center trial with a long-term follow-up (24 months) of study participants.


Eligibility

Min Age: 42 Months

Inclusion Criteria6

  • Subject is eligible for a PEEK customized implant as per routine clinical practice.
  • Subject is 12 years of age or older (Europe only).
  • Subject is 3.5 years of age or older (USA only).
  • Adult subjects able to give consent.
  • Subjects under the age of 18 will have a legal representative or parents (France - both parents must sign) to provide informed consent.
  • Subjects who are unable to give consent themselves but have a legally authorized representative that may consent on their behalf.

Exclusion Criteria7

  • Subject has an active systemic or local infection.
  • Subject has known allergy to plastic or polymers and/or known sensitivity to foreign bodies.
  • Comprised bone due to poor blood supply, disease, infection or prior implantation, which would not allow adequate support or fixation of the implant.
  • Mental or neuromuscular disorder which could create an unacceptable risk of implant instability or implant fixation failure, or complications in postoperative care.
  • Knowingly pregnant or nursing women.
  • Concomitant participation in other clinical trials related to cranioplasty.
  • Subject who has an expected survival rate of less than 2 years, in the opinion of the investigator who takes consent.

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Interventions

DEVICEStryker's PEEK Customized Implant

The PEEK Customized Implants will be used in this patient cohort for augmentation and/or restoration of bony and/or soft tissue deformities in the cranial and craniofacial skeleton (orbital rim, zygoma, and adjacent bone); including but not limited to, the correction and prevention of persistent temporal hollowing (PTH).


Locations(13)

University of Louisville 501 E. Broadway, Suite 210

Louisville, Kentucky, United States

Department of Neurological Surgery

New Brunswick, New Jersey, United States

Department of Neurological Surgery, 710 West 168th Street, 4th Floor, New York Presbyterian Hospital

New York, New York, United States

Lewis Katz School of Medicine at Temple University, 3401 North Broad Street

Philadelphia, Pennsylvania, United States

Medical University of South Carolina, Oral & Maxillofacial Surgery, 173 Ashley Avenue, Charleston, USA

Charleston, South Carolina, United States

Universitätsklinik für Neurochirurgie Auenbruggerplatz 29

Graz, Austria

Pierre-Paul Riquet Hospital, Place du Docteur Baylac, Cedex 9

Toulouse, Occitanie, France

APHP - Hôpital Lariboisière Neurochirurgie 2 rue Ambroise Paré

Paris, Paris France, France

CHU Nantes - Hopital Guillaume et Rene Laënnec, Cedex 1

Nantes, Pays de la Loire Region, France

St. Barbara-Klinik Hamm GmbH Hamm Heessen und St. Josef-Krankenhaus Hamm-Bockum-Hövel Am Heessener Wald 1 | 1263

Hamm, Hamm, Germany

Klinik für Neurochirurgie Klinikum Dortmund Münsterstr. 240

Dortmund, North Rhine-Westphalia, Germany

Servicio de Neurocirugía Hospital Universitario La Paz.

Madrid, Madrid, Spain

Neurosurgery, Emergency and Major Trauma (NET) Research | Division of Medicine | Imperial College Healthcare NHS Trust

London, London, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT05362370


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