Olfactory Training on Smell Dysfunction Patients in HK
Effect of Olfactory Training on Olfactory Dysfunction Patients in Hong Kong Population
Pamela Youde Nethersole Eastern Hospital
80 participants
Jul 1, 2022
INTERVENTIONAL
Conditions
Summary
* Causes of olfactory dysfunction can be classified into conductive and sensorineural causes. * Conductive causes are mainly due to structural nasal problem, which can be treated by nasal surgery * Sensorineural causes included post-infection, post-head injury, post Head and Neck irradiation and other central nervous system diseases. * Olfactory Training is well established treatment for sensorineural olfactory dysfunction in foreign countries. * Olfactory Training by neurological chemosensory stimulation using aromatic substances delivered via electronic portable aromatic rehabilitation (EPAR) diffuser was proved to be effective treatment in COVID-19 related olfactory dysfunction in recent Hong Kong study. * However, there is a lack of local study on the effect of Olfactory Training in other non-COVID-19 sensorineural causes of olfactory dysfunction in Hong Kong population.
Eligibility
Inclusion Criteria1
- Olfactory dysfunction \> 6 months and \< 5 years
Exclusion Criteria10
- History of significant head injury (fracture, ICH)
- History of brain surgery
- History of nasal surgery
- Active nasal disease
- Active neurological disease
- Poor premorbid status/ non-communicable patients
- Mentally incompetent patients
- \<18 years' old
- Pregnancy
- Hypersensitivity to the aromatic substance.
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Interventions
Four aromatic substances will be used (Citrus limon, Eucalyptus radiata, Pelargonium graveolens, Juniperus virginiana)
Normal Saline will be used
Locations(1)
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NCT05364125