Non-invasive Spinal Cord Stimulation for Recovery of Autonomic Function After Spinal Cord Injury

Inclusion Criteria16

• Resident of British Columbia, Canada with active provincial medical services plan.
• Male or female, 19-60 years of age.
• Chronic traumatic SCI (non-progressive, with complete motor paralysis) at or above the T6 spinal segment.
• >1-year post injury, at least 6 months from any spinal surgery.
• American Spinal Injury Association Impairment Scale (AIS) A, B.
• Stable management of spinal cord related clinical issues (i.e., spasticity management).
• Experience bladder, or bowel, or sexual dysfunction.
• No painful musculoskeletal dysfunction, unhealed fracture, pressure sore, or active infection that may interfere with testing.
• For women of childbearing potential, not intending to become pregnant, currently pregnant, or lactating. The following conditions apply:
• A confirmed negative pregnancy test prior to the baseline visit. During the trial, all women of childbearing potential will undergo urine pregnancy tests at their monthly clinic visits as outlined in the schedule of events.
• Use adequate contraception, or complete abstinence from sexual activities, during the period of the trial and for at least 28 days after completion of treatment.
• If using combined hormonal contraception, a stable regimen during the period of the trial and for at least 28 days after completion of treatment.
• For sexually active males with female partners of childbearing potential, use adequate contraception, or complete abstinence from sexual activities, during the period of the trial and for at least 28 days after completion of treatment.
• Must provide informed consent.
• Willing and able to comply with all clinic visits and study-related procedures.
• Able to understand and complete study-related questionnaires (must be able to understand and speak English or have access to an appropriate interpreter as judged by the investigator).