RecruitingNot ApplicableNCT05370079

Control Cohort CTRL COH


Sponsor

Hospices Civils de Lyon

Enrollment

350 participants

Start Date

Aug 8, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS) are rare disease that could be difficult to diagnose. So it necessary to obtain numerous sample from different disease to develop more specific diagnosis kit It could be possible through the characterisation of new genetic biomarkers.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is enrolling a control group of patients with certain neurological or non-neurological conditions to help researchers better understand rare brain diseases. By collecting samples and data from people with conditions like Parkinson's disease, ALS, glioblastoma, and certain cancers, researchers can compare them against patients with unusual neurological syndromes. **You may be eligible if...** - You have one of the following diagnoses: Parkinson's disease, ALS (amyotrophic lateral sclerosis), glioblastoma (brain cancer), a non-neurological cancer (lung, breast, ovarian, melanoma, or thymoma), or rheumatoid arthritis - You are able to give informed consent **You may NOT be eligible if...** - You refuse or are unable to give consent - You have a condition consistent with a paraneoplastic neurological syndrome or autoimmune encephalitis (a type of brain inflammation caused by the immune system) - You are under legal guardianship Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALCollection of biological sample (blood and/or CSF)

Blood sample will be collected one time for each patient: 2 \*4ml of blood on dry tube 2 \*4ml of blood on EDTA tube If cerebrospinal fluid (CSF) has been drawn for diagnosis, remaining sample available will be stored in the control cohort (1 ml).


Locations(1)

Hospices Civils de Lyon

Bron, France

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NCT05370079