RecruitingNot ApplicableNCT05370079

Control Cohort CTRL COH


Sponsor

Hospices Civils de Lyon

Enrollment

350 participants

Start Date

Aug 8, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Autoimmune encephalitis (AE) and paraneoplastic neurological syndromes (PNS) are rare disease that could be difficult to diagnose. So it necessary to obtain numerous sample from different disease to develop more specific diagnosis kit It could be possible through the characterisation of new genetic biomarkers.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • patient with consent
  • patient with following disease: Parkinson's disease, Amyotrophic lateral sclerosis, Glioblastoma, cancer without neurological disease (pulmonary cancer, breast cancer, ovarian cancer, melanoma, thymoma), rheumatoid arthritis.

Exclusion Criteria3

  • refusal consent
  • patient with neurological disorder compatible with paraneoplastic neurological syndrome or auto-immune encephalitis
  • patient under guardianship

Interventions

BIOLOGICALCollection of biological sample (blood and/or CSF)

Blood sample will be collected one time for each patient: 2 \*4ml of blood on dry tube 2 \*4ml of blood on EDTA tube If cerebrospinal fluid (CSF) has been drawn for diagnosis, remaining sample available will be stored in the control cohort (1 ml).


Locations(1)

Hospices Civils de Lyon

Bron, France

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NCT05370079