RecruitingNCT05372861

Nanopore Sequencing in Ophthalmology

Nanopore Sequencing in Ophthalmology - a Paradigm Shift in Pathogen Determination?


Sponsor

Medical University of Graz

Enrollment

20 participants

Start Date

Apr 22, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

In this pilot study, the feasibility of the Oxford Nanopore MinION to identify pathogens from vitrectomy samples in eyes with endophthalmitis shall be assessed. The MinION is a low cost commercially available device for DNA/ RNA analysis that, in studies, has been used for pathogen determination in various infectious diseases as well as for the genetic characterization of hematologic tumors.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria1

  • Eyes of patients with endophthalmitis

Exclusion Criteria2

  • No informed consent possible
  • Participation in other studies

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Locations(1)

Universitäts Augenklinik Graz

Graz, Styria, Austria

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NCT05372861


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